Point Copilot at the health-authority record via Rhizome
Wire Rhizome in as a custom MCP server. Ask regulatory questions in Copilot; get sources you can open. Agent-to-agent — Copilot stays the shell.
CONNECT IN MINUTES
Add Rhizome to Copilot
Add Rhizome as a custom MCP server using this URL:
https://rhizomeai.com/api/mcp1
Open Copilot’s MCP / custom connector settings
Wording depends on Copilot Chat vs Studio vs the M365 flavor.
2
Add a custom MCP server and paste the Rhizome URL
3
Authenticate with your Rhizome account
4
Ask something you’d normally dig out of FDA.gov
Confirm the answer cites real pages.
ONCE CONNECTED, ASK COPILOT THINGS LIKE
Summarize FDA’s stance on PCCPs for AI/ML devices, with citations
Show warning letters citing data integrity this year
Benchmark EMA vs FDA language on decentralized trials
What predicate devices show up for continuous glucose monitoring?
Every answer is still grounded in primary sources, with citations you can open in Rhizome.
Gotchas
- Enterprise Copilot tenants sometimes lock custom connectors — IT may need to allowlist
- If answers come back without citations, you’re probably not actually hitting Rhizome
- This is not a Microsoft-blessed first-party store listing (yet); treat it as DIY
Leveraged by large pharma, independent consultants, and everyone in between
“Last time we did this research, we spent weeks. Rhizome found the answer immediately.”
“Chetan idk what kind of magic you all did here, it's so good!”
“I want this. I'm really impressed by the quality of the information and the level of detail.”